Bird flu, also known as avian influenza, has been a significant public health concern globally. The H5N1 strain has caused widespread outbreaks in poultry and wild birds, with sporadic human infections reported in 24 countries since 1997. In the United States, a recent multistate outbreak among cows has led to three dairy workers being infected, marking the first cow-to-human transmissions. Experts emphasize the need for heightened surveillance and testing to monitor the situation, as the virus has shown adaptability in jumping from species to species.