AZ Cardinals vs SF 49ers
16
AZ Cardinals
No
AZ Cardinals
No
SF 49ers
Yes
SF 49ers
Yes
Spread and Total
SF 49ers win by over33.5points
No
SF 49ers win by over33.5points
33.5
30.5
27.5
23.5
20.5
17.5
16.5
14.5
13.5
10.5
9.5
8.5
7.5
6.5
5.5
4.5
3.5
2.5
1.5
1.5
2.5
3.5
4.5
5.5
6.5
7.5
9.5
10.5
13.5
14.5
No
Over26.5points
Yes
Over26.5points
26.5
29.5
32.5
35.5
38.5
41.5
44.5
45.5
46.5
47.5
48.5
49.5
50.5
53.5
56.5
59.5
62.5
65.5
68.5
Yes
Team Totals
SF 49ers over3.5points scored
Yes
SF 49ers over3.5points scored
3.5
7.5
10.5
14.5
17.5
20.5
21.5
24.5
28.5
31.5
35.5
38.5
42.5
Yes
ARI Cardinals over3.5points scored
Yes
ARI Cardinals over3.5points scored
3.5
7.5
10.5
14.5
17.5
19.5
20.5
21.5
24.5
28.5
31.5
35.5
38.5
42.5
Yes
Head-to-head
Every 49ers vs Cardinals meeting on the schedule
The games these two clubs play against each other — still to come first, then already played — with the Kalshi market for any that is listed.Sun, Jan 10 · time TBD
Sun, Sep 27 · 4:05 PM ETSan Francisco 49ers
Arizona Cardinals
NFL · Week 18
Arizona Cardinals
30
San Francisco 49ers
36
NFL · Week 3
Upcoming
Next games for the 49ers and Cardinals
Every fixture either club plays next, whoever the opponent is, with the Kalshi market where one is listed.Sun, Oct 11 · 4:25 PM ET
San Francisco 49ers
Seattle Seahawks
NFL · Week 5
Sun, Oct 11 · 4:25 PM ETDetroit Lions
Arizona Cardinals
NFL · Week 5
Sun, Oct 18 · 4:05 PM ET
Arizona Cardinals
Los Angeles Rams
NFL · Week 6
Mon, Oct 19 · 8:15 PM ET
Washington Commanders
San Francisco 49ers
NFL · Week 6
Sun, Oct 25 · 1:00 PM ET
San Francisco 49ers
Atlanta Falcons
NFL · Week 7
Sun, Oct 25 · 4:05 PM ET
Denver Broncos
Arizona Cardinals
NFL · Week 7
Sun, Nov 1 · 1:00 PM ET
Arizona Cardinals
Dallas Cowboys
NFL · Week 8
Sun, Nov 8 · 4:05 PM ET
Las Vegas Raiders
San Francisco 49ers
NFL · Week 9
Sun, Nov 8 · 4:25 PM ET
Arizona Cardinals
Seattle Seahawks
NFL · Week 9
Sun, Nov 15 · 4:05 PM ET
Los Angeles Rams
Arizona Cardinals
NFL · Week 10
Recent form
Recent games for the 49ers and Cardinals
The last games each club played, whoever the opponent was — with the final score where one is available, and the market page for any that Kalshi listed.Sun, Oct 4 · 4:25 PM ET
Denver Broncos
14
San Francisco 49ers
24
NFL · Week 4
Sun, Oct 4 · 1:00 PM ETArizona Cardinals
24
New York Giants
36
NFL · Week 4
Sun, Sep 27 · 4:05 PM ETArizona Cardinals
30
San Francisco 49ers
36
NFL · Week 3
Sun, Sep 20 · 4:25 PM ETMiami Dolphins
13
San Francisco 49ers
35
NFL · Week 2
Sun, Sep 20 · 4:25 PM ETSeattle Seahawks
31
Arizona Cardinals
7
NFL · Week 2
Around the league
Other games this week
The rest of that week's league slate, without these two clubs, so the next thing to trade is one click away.Mon, Oct 12 · 8:15 PM ET
Buffalo Bills
Los Angeles Rams
NFL · Week 5
Thu, Oct 8 · 8:15 PM ETTampa Bay Buccaneers
Dallas Cowboys
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETMinnesota Vikings
New Orleans Saints
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETNew York Giants
Washington Commanders
NFL · Week 5
Sun, Oct 11 · 4:25 PM ETChicago Bears
Green Bay Packers
NFL · Week 5
Sun, Oct 11 · 9:30 AM ETPhiladelphia Eagles
Jacksonville Jaguars
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETCincinnati Bengals
Miami Dolphins
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETCleveland Browns
New York Jets
NFL · Week 5
FAQ
49ers vs Cardinals questions
When do the 49ers and Cardinals play next?
The San Francisco 49ers and the Arizona Cardinals meet twice in the 2026 regular season: Week 3 in San Francisco and Week 18 in Arizona. Kickoff times come from the NFL’s published schedule and are shown in Eastern time. A game the league flexes keeps its week while its day and time move, so it shows a date without a time until the slot is fixed.
Are the 49ers and Cardinals in the same division?
Yes. The San Francisco 49ers and the Arizona Cardinals both play in the NFC West. Six of every NFL club’s games are inside its own division — the other three opponents, home and away — so 49ers vs Cardinals is one of the six pairings that division is made of.
What is at stake when the 49ers play the Cardinals?
The NFC West, potentially. Head-to-head record is the first tiebreaker the NFL applies between two clubs that finish level in the same division, so if the 49ers and the Cardinals end the season on the same record these two games settle it between them. Division record is the tiebreaker after that, and both of them are division games too.
Can the 49ers and Cardinals meet in the playoffs?
Yes. The 49ers and the Cardinals share a division and therefore a conference, so the bracket can pair them in the wild-card round, the divisional round or the NFC Championship Game — a third meeting on top of the two the regular season already guarantees.
How often do the 49ers and Cardinals play each other?
Every season, twice — once at each club’s stadium. Division opponents are the fixed part of an NFL schedule, so for as long as the 49ers and the Cardinals are both in the NFC West the pairing is on the calendar every year, whatever else the rotation brings.
Where can I follow the 49ers and Cardinals for the rest of the season?
Each club has its own page on Kalshi. The San Francisco 49ers and Arizona Cardinals hubs carry the roster, the weekly injury report, the remaining schedule, the division standings and the market’s read on each club’s division, playoff and Super Bowl chances.