DET Lions vs BUF Bills
16
DET Lions
No
DET Lions
No
BUF Bills
Yes
BUF Bills
Yes
Spread and Total
BUF Bills wins by over33.5points
No
BUF Bills wins by over33.5points
33.5
30.5
27.5
23.5
20.5
17.5
16.5
14.5
13.5
10.5
9.5
7.5
6.5
5.5
4.5
3.5
2.5
1.5
1.5
2.5
3.5
4.5
5.5
6.5
7.5
9.5
10.5
13.5
14.5
No
Over30.5points scored
Yes
Over30.5points scored
30.5
33.5
36.5
39.5
42.5
45.5
48.5
49.5
50.5
51.5
52.5
53.5
54.5
57.5
60.5
63.5
66.5
69.5
72.5
75.5
78.5
Yes
Team Totals
BUF Bills over3.5points scored
Yes
BUF Bills over3.5points scored
3.5
7.5
10.5
14.5
17.5
20.5
21.5
24.5
28.5
29.5
31.5
35.5
38.5
42.5
45.5
48.5
51.5
54.5
Yes
DET Lions over3.5points scored
Yes
DET Lions over3.5points scored
3.5
7.5
10.5
14.5
17.5
20.5
21.5
24.5
28.5
31.5
35.5
38.5
42.5
Yes
Head-to-head
Every Bills vs Lions meeting on the schedule
The games these two clubs play against each other — still to come first, then already played — with the Kalshi market for any that is listed.Upcoming
Next games for the Bills and Lions
Every fixture either club plays next, whoever the opponent is, with the Kalshi market where one is listed.Sun, Oct 11 · 4:25 PM ET
Detroit Lions
Arizona Cardinals
NFL · Week 5
Mon, Oct 12 · 8:15 PM ETBuffalo Bills
Los Angeles Rams
NFL · Week 5
Sun, Oct 18 · 4:25 PM ET
Buffalo Bills
Las Vegas Raiders
NFL · Week 6
Sun, Oct 25 · 4:25 PM ET
Green Bay Packers
Detroit Lions
NFL · Week 7
Sun, Nov 1 · 1:00 PM ET
Baltimore Ravens
Buffalo Bills
NFL · Week 8
Sun, Nov 1 · 1:00 PM ET
Minnesota Vikings
Detroit Lions
NFL · Week 8
Sun, Nov 8 · 1:00 PM ET
Detroit Lions
Miami Dolphins
NFL · Week 9
Mon, Nov 9 · 8:15 PM ET
Buffalo Bills
Minnesota Vikings
NFL · Week 9
Sun, Nov 15 · 9:30 AM ET
New England Patriots
Detroit Lions
NFL · Week 10
Sun, Nov 15 · 1:00 PM ET
Buffalo Bills
New York Jets
NFL · Week 10
Recent form
Recent games for the Bills and Lions
The last games each club played, whoever the opponent was — with the final score where one is available, and the market page for any that Kalshi listed.Sun, Oct 4 · 8:20 PM ET
Detroit Lions
26
Carolina Panthers
32
NFL · Week 4
Sun, Oct 4 · 1:00 PM ETNew England Patriots
29
Buffalo Bills
26
NFL · Week 4
Sun, Sep 27 · 1:00 PM ETLos Angeles Chargers
16
Buffalo Bills
24
NFL · Week 3
Sun, Sep 27 · 1:00 PM ETNew York Jets
24
Detroit Lions
31
NFL · Week 3
Thu, Sep 17 · 8:15 PM ETDetroit Lions
31
Buffalo Bills
41
NFL · Week 2
Around the league
Other games this week
The rest of that week's league slate, without these two clubs, so the next thing to trade is one click away.Sun, Oct 11 · 4:25 PM ET
Chicago Bears
Green Bay Packers
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETCincinnati Bengals
Miami Dolphins
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETCleveland Browns
New York Jets
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETLas Vegas Raiders
New England Patriots
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETMinnesota Vikings
New Orleans Saints
NFL · Week 5
Thu, Oct 8 · 8:15 PM ETTampa Bay Buccaneers
Dallas Cowboys
NFL · Week 5
Sun, Oct 11 · 9:30 AM ETPhiladelphia Eagles
Jacksonville Jaguars
NFL · Week 5
Sun, Oct 11 · 1:00 PM ETHouston Texans
Tennessee Titans
NFL · Week 5
FAQ
Bills vs Lions questions
When do the Bills and Lions play next?
The Buffalo Bills and the Detroit Lions meet once in the 2026 regular season: Week 2 in Buffalo. Kickoff times come from the NFL’s published schedule and are shown in Eastern time. A game the league flexes keeps its week while its day and time move, so it shows a date without a time until the slot is fixed.
Are the Bills and Lions in the same division?
No, and not the same conference either. The Buffalo Bills play in the AFC East and the Detroit Lions in the NFC North — one an AFC club, the other NFC. That makes any meeting between them an interconference game, which the league schedules on a rotation rather than every season.
What is at stake when the Bills play the Lions?
For the Bills and the Lions, the overall record and only that. An interconference game touches neither club’s division record nor its conference record — but the overall record is where every seeding decision starts, and it feeds the strength-of-victory measures the league falls back on when nothing closer separates two clubs.
Can the Bills and Lions meet in the playoffs?
Only in the Super Bowl. The Bills are in the AFC and the Lions in the NFC, and the playoffs are run inside each conference until the final — so these two cannot be drawn against each other before it.
How often do the Bills and Lions play each other?
Rarely. AFC and NFC divisions are matched in full once every four seasons, so the AFC East and the NFC North meet on that rotation. Outside it, the single interconference game each club plays against a same-position finisher can bring the Bills and the Lions together sooner.
Where can I follow the Bills and Lions for the rest of the season?
Each club has its own page on Kalshi. The Buffalo Bills and Detroit Lions hubs carry the roster, the weekly injury report, the remaining schedule, the division standings and the market’s read on each club’s division, playoff and Super Bowl chances.